© 2016 Japanese Dermatological Association. In the current systematic review we evaluated the accuracy of sentinel lymph node biopsy for inguinal lymph node staging of penile squamous cell carcinoma and studied possible influential factors. Objective: To review the results of SLNB for patients with cSCC of the head and neck at the authors institution. In conclusion, in this small retrospective cohort, in patients with cutaneous squamous cell carcinoma, there were no significant differences in metastasis-free and disease-specific survival rates between those who did or did not undergo sentinel lymph node biopsy, regardless of T staging.Ĭutaneous squamous cell carcinoma elderly false-negative prognosis sentinel lymph node biopsy. Background: Limited data exist on sentinel lymph node biopsy (SLNB) for cutaneous squamous cell carcinoma (cSCC) of the head and neck. The benefit of sentinel lymph node biopsy in improving cutaneous squamous cell carcinoma prognosis is doubtful. When selecting for those with T2 tumors or greater, the same lack of relationship was observed. Patients with T2-T4 tumors had a higher risk compared with those with T1 tumors. Patients with clinical lymph node metastases had a higher risk compared with those without. The role of sentinel lymph node (SLN) biopsy in these patients remains unclear. The metastasis-free and disease-specific survival rates were not significantly different in those who did or did not undergo sentinel lymph node biopsy. High-risk cutaneous squamous cell carcinoma (SCC) is associated with an increased risk of metastases. Among the 107 patients who did not undergo lymph node biopsy, 12 (11.2%) developed post-treatment metastases. Of these 49 patients, nine (18.4%) presented with sentinel lymph node metastasis, which occurred after treatment in three (6.1%) of them (false-negative).
Forty-nine patients underwent sentinel lymph node biopsy, whereas 120 patients did not, including 13 who exhibited clinical lymph node metastases before treatment. Management of the neck in early-stage (T1-T2) clinically node-negative (N0) oral squamous cell carcinoma (OSCC) has considerably evolved over time. One hundred and sixty-nine patients who underwent treatment for cutaneous squamous cell carcinoma between 20, and who were followed up for at least 6 months or developed metastases within the follow-up period were included. The benefit of sentinel lymph node biopsy in improving cutaneous squamous cell carcinoma prognosis is doubtful. Sentinel lymph node biopsy is generally performed in breast cancers and cutaneous melanomas to detect occult nodal metastases. Cutaneous squamous cell carcinoma is the second common cutaneous cancer, especially in the elderly.
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